Beschreibung
To strengthen our excellent research team, which is focused on the development and research of innovative approaches for the treatment of childhood cancer, we are looking for a PhD student (m/f/d) working on tumor immunoediting to work on tumor immunoediting. In this responsible role, you will have the unique opportunity to be part of a multidisciplinary competence center for pediatric oncology and to have a direct influence on the development of new cancer therapies.
Our group (https://http://www.ccri.at/eva-koenig-group/) studies the role of natural killer cells in tumor immunoediting and aims to identify the molecular mechanisms of tumor immune evasion in order to find novel therapeutic targets against leukemia with sustained success. We use DNA barcoding technologies, multiomics approaches (single-cell and bulk RNA-seq, ATAC-seq), genome editing (CRISPR/Cas9 gene knockout in cell lines, siRNA knock-down in primary immune cells), mouse models and a diverse array of in vitro functional studies (including multi-color flow cytometry). The project is funded by a FWF stand-alone grant and aims to find novel therapeutic targets to increase the immunogenicity of tumor cells and/or to improve NK cell functionality.
Your responsibilities
Join an exciting, multi-disciplinary environment with lots of support for your personal and professional development from your supervisor, team, and peers
Learn to take on ambitious research in close collaboration with team members and expert collaboration partners
You will contribute from the start including the planning of experiments and data acquisition
You will provide thorough and creative thinking that will make these projects successful
Monitor the literature and community resources to stay abreast of the latest developments and to identify information, data, and methods to integrate into your own work
Write papers, present your research at conferences, apply for fellowships, and contribute to grants
Your profile
Master’s degree in a relevant subject (e.g. molecular biology, genetics, microbiology, biotechnology)
Excellent technical skills (cell culture, molecular biology methods, first experience with mouse models would be advantageous but not required)
Motivation to pursue an ambitious research agenda
Excellent verbal and written communication skills in English (German not required)
Self-motivated, enthusiastic and eager to learn
Good team player, committed, and creative
Scientific mindset, a problem solving attitude
Our offer
A meaningful, inspiring, and international environment
An outstanding working atmosphere in a strong team with excellent research and development opportunities
Focus on medically relevant problems, with a strong translational aspect and close collaboration with physicians and the clinical trial unit
Access to state-of-the-art infrastructure
A multi-dimensional approach and the possibility to learn a diverse methodological skill set
Flexible working hours, discounted lunch in our canteen and other great benefits
Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
A fair and attractive salary package according to the Austrian Science Fund FWF (https://http://www.fwf.ac.at/en/research-funding/personnel-costs/)
Who we are
The St. Anna Children’s Cancer Research Institute (CCRI), located in the center of Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences, is an international and multidisciplinary competence center striving to improve treatment of children and adolescents with cancer by connecting translational and clinical research with open-minded exploration of basic disease mechanisms. Through close cooperation between clinic and research, the CCRI provides an ideal environment for cutting-edge research and its translation into clinical practice. To achieve our ultimate goal of advancing the well-being of patients, the CCRI constantly pushes scientific boundaries and strongly promotes close collaboration and exchange with external institutions like the Medical University of Vienna, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) and the Institute of Molecular Pathology (IMP).
The CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to ethnicity, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.
Find more information here: or .
Your application
We are looking forward to your application! Applications should at least contain your Curriculum Vitae, a cover letter, list of publications (please mark / explain your three top contributions), and the contact details of three references. The deadline for the application is 26th of July 2021 but applications will be reviewed on a rolling basis until the position is filled.
Please apply via this link:
Eckdaten
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